diff --git a/Marlin/Configuration.h b/Marlin/Configuration.h
index 663f9504b9..7d4863d58c 100644
--- a/Marlin/Configuration.h
+++ b/Marlin/Configuration.h
@@ -2642,7 +2642,9 @@
 // packaged with Marlin. Source code for the user interface will need to
 // be placed in "src/lcd/extensible_ui/lib"
 //
-//#define EXTENSIBLE_UI
+#if ENABLED(MachineCR10SPro) && DISABLED(GraphicLCD)
+  #define EXTENSIBLE_UI
+#endif
 
 //=============================================================================
 //=============================== Graphical TFTs ==============================