diff --git a/Marlin/Configuration.h b/Marlin/Configuration.h
index 25604a6c77..c12bed8afd 100644
--- a/Marlin/Configuration.h
+++ b/Marlin/Configuration.h
@@ -79,7 +79,7 @@
  *
  * :[-1, 0, 1, 2, 3, 4, 5, 6, 7]
  */
-#define SERIAL_PORT -1
+#define SERIAL_PORT 0
 
 /**
  * Serial Port Baud Rate
@@ -101,7 +101,7 @@
  * Currently Ethernet (-2) is only supported on Teensy 4.1 boards.
  * :[-2, -1, 0, 1, 2, 3, 4, 5, 6, 7]
  */
-#define SERIAL_PORT_2 0
+#define SERIAL_PORT_2 1
 //#define BAUDRATE_2 250000   // :[2400, 9600, 19200, 38400, 57600, 115200, 250000, 500000, 1000000] Enable to override BAUDRATE
 
 /**
@@ -139,11 +139,11 @@
  *          TMC5130, TMC5130_STANDALONE, TMC5160, TMC5160_STANDALONE
  * :['A4988', 'A5984', 'DRV8825', 'LV8729', 'TB6560', 'TB6600', 'TMC2100', 'TMC2130', 'TMC2130_STANDALONE', 'TMC2160', 'TMC2160_STANDALONE', 'TMC2208', 'TMC2208_STANDALONE', 'TMC2209', 'TMC2209_STANDALONE', 'TMC26X', 'TMC26X_STANDALONE', 'TMC2660', 'TMC2660_STANDALONE', 'TMC5130', 'TMC5130_STANDALONE', 'TMC5160', 'TMC5160_STANDALONE']
  */
-#define X_DRIVER_TYPE  TB6600
-#define Y_DRIVER_TYPE  TB6600
+#define X_DRIVER_TYPE  TMC5160_STANDALONE
+#define Y_DRIVER_TYPE  TMC5160_STANDALONE
 #define Z_DRIVER_TYPE  TB6600
 //#define X2_DRIVER_TYPE A4988
-#define Y2_DRIVER_TYPE TB6600
+#define Y2_DRIVER_TYPE TMC5160_STANDALONE
 #define Z2_DRIVER_TYPE TB6600
 #define Z3_DRIVER_TYPE TB6600
 #define Z4_DRIVER_TYPE TB6600
@@ -392,7 +392,7 @@
  * Enable and connect the power supply to the PS_ON_PIN.
  * Specify whether the power supply is active HIGH or active LOW.
  */
-#define PSU_CONTROL
+//#define PSU_CONTROL
 //#define PSU_NAME "Power Supply"
 
 #if ENABLED(PSU_CONTROL)
@@ -2734,7 +2734,7 @@
 // If you have a speaker that can produce tones, enable it here.
 // By default Marlin assumes you have a buzzer with a fixed frequency.
 //
-#define SPEAKER
+//#define SPEAKER
 
 //
 // The duration and frequency for the UI feedback sound.